PTR-MS in medicine

Ionimed Publications:

Beauchamp et al 2010 Characterization of an olfactometer by proton-transfer-reaction mass spectrometry, Meas. Sci. Technol. 21 (2010) 025801. (9pp) doi: 10.1088/1752-7155/3/2/027004

Herbig et al 2009 On-line breath analysis with PTR-TOF, J. Breath Res. 3 (2009) 027004. (10pp) doi: 10.1088/1752-7155/3/2/027004

Kohl et al 2009 Proton-Transfer-Reaction Mass Spectrometry real-time analysis of volatile organic compounds in the exhaled breath: kidney transplant rejection diagnosis, 4th International Conference on Proton Tansfer Reaction Mass Spectrometry and its Applications. Eds: A.Hansel, J. Dunkl, Innsbruck University Press, ISBN 978-3-902571-99-1, pp. 251

Beauchamp et al 2008 On the use of Tedlar® bags for breath-gas sampling and analysis J. Breath Res. 2 (2008) 046001 (19pp)doi:10.1088/1752-7155/2/4/046001

Herbig et al 2008 Buffered end-tidal (BET) sampling - a novel method for real-time breath-gas analysis J. Breath Res. 2 (2008) 037008 (9pp) doi:10.1088/1752-7155/2/3/037008

Other Publications:

J. Breath Res. 3: special issue (2009), guest editor Jens Herbig (Editorial):

O’Hara et al 2009 A preliminary comparison of volatile organic compounds in the headspace of cultures of Staphylococcus aureus grown in nutrient, dextrose and brain heart bovine broths measured using a proton transfer reaction mass spectrometer J. Breath Res. 3 (2009) 027001 (8pp) doi:10.1088/1752-7155/3/2/027001

Schwarz et al 2009 Determining concentration patterns of volatile compounds in exhaled breath by PTR-MS J. Breath Res. 3 (2009) 027002 (15pp) doi:10.1088/1752-7155/3/2/027002

Schwarz et al 2009 Breath acetone—aspects of normal physiology related to age and gender as determined in a PTR-MS study J. Breath Res. 3 (2009) 027003 (9pp) doi:10.1088/1752-7155/3/2/027003

O’Hara et al 2009 Endogenous volatile organic compounds in breath and blood of healthy volunteers: examining breath analysis as a surrogate for blood measurements J. Breath Res. 3 (2009) 027005 (10pp) doi:10.1088/1752-7155/3/2/027005

King et al 2009 Isoprene and acetone concentration profiles during exercise on an ergometer J. Breath Res. 3 (2009) 027006 (16pp) doi:10.1088/1752-7155/3/2/027006

Thekedar et al 2009 Investigations on the variability of breath gas sampling using PTR-MS J. Breath Res. 3 (2009) 027007 (11pp) doi:10.1088/1752-7155/3/2/027007

O’Hara et al 2008 Development of a protocol to measure volatile organic compounds in human breath: a comparison of rebreathing and on-line single exhalations using proton transfer reaction mass spectrometry Physiol. Meas. 29 309–30 doi:10.1088/0967-3334/29/3/003

Kushch et al 2008 Compounds enhanced in a mass spectrometric profile of smokers’ exhaled breath versus non-smokers as determined in a pilot study using PTR-MS J. Breath Res. 2 026002 doi:10.1088/1752-7155/2/2/026002

Steeghs et al 2007 An off-line breath sampling and analysis method suitable for large screening studies Physiol. Meas. 28 503-14 doi:10.1088/0967-3334/28/5/005

Steeghs et al 2007 The suitability of Tedlar bags for breath sampling in medical diagnostic research Physiol. Meas. 28 73-84 doi:10.1088/0967-3334/28/5/005

Wehinger et al 2007 Lung cancer detection by proton transfer reaction mass-spectrometric analysis of human breath gas Int. J. Mass Spectrom. 265 49-59 doi:10.1016/j.ijms.2007.05.012

Amann et al 2004 Applications of breath gas analysis in medicine Int. J Mass Spectrom. 239 227–33 doi:10.1016/j.ijms.2004.08.010

Harrison et al 2003 Real-time breath monitoring of propofol and its volatile metabolites during surgery using a novel mass spectrometric technique: a feasibility study Br. J. Anaesth. 91(6) 797-9 doi:10.1093/bja/aeg271

Karl et al 2001 Human breath isoprene and its relation to blood cholesterol levels: new measurements and modeling J. Appl. Physiol. 91 762-70 doi:

Lindinger et al 1998 On-line monitoring of volatile organic compounds at pptv levels by means of proton-transfer-reaction mass spectrometry (PTR-MS) medical applications, food control and environmental research Int. J. Mass Spectrom. Ion Proc. 173 191-241 doi:10.1016/S0168-1176(97)00281-4

Taucher et al 1997 Detection of isoprene in expired air from human subjects using proton-transfer-reaction mass spectrometry Rapid Commun. Mass Spectrom. 11 1230-4 journal

Hansel et al 1995 Proton transfer reaction mass spectrometry: on-line trace gas analysis at the ppb level Int. J. Mass Spectrom. Ion Proc. 149/150 609-19 doi:10.1016/0168-1176(95)04294-U

Jordan et al 1995 Acetonitrile and benzene in the breath of smokers and non-smokers investigated by proton transfer reaction mass spectrometry (PTR-MS) Int. J. Mass Spectrom. Ion Process. 148 L1-3 doi:10.1016/0168-1176(95)04236-E

PTR-MS in biotechnology

Ionimed Publications:

Seewald et al (2010) Substrate-induced volatile organic compound emissions from compost-amended soils. Biology and Fertility of Soils.

Singer et al (2010) PTR-MS Technology for Process Monitoring and Control in Biotechnology.Process Analytical Chemistry.

Bunge et al (2008) On-Line PTR-MS Monitoring of Volatile Metabolites in the Dynamic Headspace of Microbial Cultures Applied & Environmental Microbiology. Published online. doi:10.1128/AEM.02069-07

POSTER: Bunge et al. (2007). An On-line PTR-MS System for the Sensitive Real-time Detection of Volatile Metabolites from Microbial Cultures.

Other Publications:

Clementschitsch and Bayer (2006) Review: Improvement of bioprocess monitoring: development of novelconcepts Microbial Cell Factories 5:19 doi:10.1186/1475-2859-5-19

GCU 

Ionimed Publications: 

Singer et al. (2007). Dynamic Gas Dilution System for Accurate Calibration of Analytical Instruments such as PTR-MS. 3rd International Conference onProton Tansfer Reaction Mass Spectrometry and its Applications. Eds: A.Hansel, T.D. Märk, Innsbruck University Press, pp. 232-237